Buy Voltaren Online

Voltaren tablets are used in cases when the pain is not too intense. It is used for pain associated with inflammatory and metabolic processes in the joints and spine, after surgeries and injuries, toothache and earache, and in many other cases.

The main mechanism of action of diclofenac established under experimental conditions, it is believed inhibition of prostaglandin biosynthesis. Prostaglandins play a major role in the genesis of inflammation, pain and fever.

In rheumatic diseases inflammatory and analgesic properties of Voltaren provide clinical effect, characterized by a significant reduction in the severity of disease manifestations as pain at rest and in motion, morning stiffness and swelling of joints, as well as the improvement of the functional state.

 

In post-traumatic and postoperative inflammatory phenomena Voltaren rapidly relieves pain (arising both at rest and in motion), to reduce the inflammatory edema and swelling of the surgical wound.

When applying Voltaren tablets and suppositories showed apparent analgesic effect of the drug for moderate to severe pain rheumatic origin. In applying the drug in the form of a solution for i / m injection drug effect occurs within 1-15 minutes. It was also found that the Voltaren capable of lowering the pain and reduce blood loss in primary dysmenorrhea.

Moreover, attacks of migraine facilitates Voltaren (when used in suppositories).

Judging from the number output from the urine unchanged diclofenac and its hydroxylated metabolites after administration of long-acting tablets, coated, and is released from it absorbed the same amount of active substance is of conventional tablets, enteric-coated shell. Nevertheless, the systemic bioavailability of diclofenac released from the tablets with prolonged action, averaging 82% of the value of the same index after taking the tablets coated in the same dose. This is perhaps another manifestation of the effect of "first pass" through the liver for dosage forms with sustained release of the active substance. Because active substance is released from the tablet slowly prolonged action, the Cmax plasma diclofenac less than in the case of administration, tablets coated with enteric coating.

Within 24 hours of observation after ingestion prolonged action tablets 100 mg diclofenac concentration in plasma is on average 13 ng / ml (40 nmol / L). The extent of absorption is directly dependent on the dose of the drug.

Because the "first pass" through the liver is metabolized about half the amount of diclofenac, AUC after administration of long-acting tablet is approximately 2 times smaller than in the case of parenteral administration, the dose equivalent.

Action Voltaren tablets

Voltaren tablets are nonsteroidal anti-inflammatory agents. The preparation contains diclofenac sodium, which is a substance having a nonsteroidal structure. He has a marked antipyretic, analgesic and anti-inflammatory effect. The primary mechanism of action appears diclofenac inhibition of biosynthesis of prostaglandins, which are important in the genesis of inflammation, fever and pain. Voltaren tablets use and contraindications.

In the case of rheumatic diseases inflammatory and analgesic properties of Voltaren provided clinical benefit, which is characterized by a significant reduction in the severity of the complaints of pain at rest and during motion, morning stiffness and swelling of joints, and improved joint function. In the treatment of inflammatory phenomena arising after injuries and operations, Voltaren rapidly cropped pain, decreases inflammatory edema and swelling that accompanies the post-operative field.

If you have moderate to severe pain, having nonrheumatic drug has a significant analgesic effect. Voltaren Tablets can be eliminated pain and reduced blood loss severity in the event of primary dysmenorrhea. In addition, the influence of Voltaren tablets have a beneficial effect on the symptoms of migraine attacks.

Voltaren contains diclofenac sodium, a substance non-steroidal structure, has a pronounced anti-inflammatory, analgesic and antipyretic effect. The main mechanism of action of diclofenac is the inhibition of the biosynthesis of prostaglandins, which play an important role in the pathogenesis of inflammation, pain and fever. In rheumatic diseases Voltaren, showing an anti-inflammatory and analgesic effects, significantly reduces pain at rest and in motion, morning stiffness and swelling of joints and improve joint function.

Diclofenac sodium does not suppress the biosynthesis of cartilage proteoglycan.In post-traumatic and postoperative inflammatory phenomena Voltaren relieves pain (both spontaneous and arose when driving), reduces inflammatory swelling and post-operative swelling of the field.Revealed a significant analgesic effect of the drug in moderate to severe pain syndrome nonrheumatic. Also found that Voltaren able to eliminate pain and reduce blood loss in primary dysmenorrhea. Voltaren also has a beneficial effect on the symptoms of migraine attacks.